Elgzyri T, Larsson J, Thörne J, Eriksson KF, Apelqvist J, et al.
European journal of vascular and endovascular surgery : the official journal of the European So.... Date of publication 2013 Jul 1;volume 46(1):110-7.
1. Eur J Vasc Endovasc Surg. 2013 Jul;46(1):110-7. doi: 10.1016/j.ejvs.2013.04.013.
Epub 2013 May 1.
Outcome of ischemic foot ulcer in diabetic patients who had no invasive vascular
intervention.
Elgzyri T(1), Larsson J, Thörne J, Eriksson KF, Apelqvist J.
Author information:
(1)Department of Endocrinology, Skåne University Hospital, Malmö, Sweden.
targ.elgzyri@med.lu.se
Erratum in
Eur J Vasc Endovasc Surg. 2014 Sep;48(3):350.
OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients
not available for revascularisation. Our aim was to identify factors related to
ulcer healing in diabetic patients with severe peripheral arterial disease who
were not available for revascularisation.
METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a
multidisciplinary foot centre with systolic toe pressure <45 mmHg or an ankle
pressure <80 mmHg were prospectively included. Patients who received
revascularisation were excluded. All patients had continuous follow-up until
healing or death.
RESULTS: Out of 602 patients (median age: 76 years) included in this study, 50%
healed either primarily (76%) or with a minor amputation (24%). Seventeen percent
of patients healed after major amputation and 33% died unhealed. By regression
analysis, rest pain, impaired renal function, ischemic heart disease, cerebral
vascular disease, extent of tissue destruction, and ankle pressure >50 mmHg
affected the outcome of the ulcers.
CONCLUSION: Diabetic patients with ischemic foot ulcers not available for
revascularisations are not excluded from healing without major amputation.
Factors strongly related to outcome were co-morbidity, severity of peripheral
arterial disease, and extent of tissue destruction. Our findings reinforce the
need for a classification system considering these factors at decision-making for
vascular intervention.
Copyright © 2013 European Society for Vascular Surgery. Published by Elsevier
Ltd. All rights reserved.
DOI: 10.1016/j.ejvs.2013.04.013
PMID: 23642521 [Indexed for MEDLINE]
