Peñas PF, Zaman S, et al.
The Australasian journal of dermatology. Date of publication 2010 Feb 1;volume 51(1):1-10; quiz 11.
1. Australas J Dermatol. 2010 Feb;51(1):1-10; quiz 11. doi:
10.1111/j.1440-0960.2009.00577.x.
Many faces of graft-versus-host disease.
Peñas PF(1), Zaman S.
Author information:
(1)Department of Dermatology, Westmead Hospital, University of Sydney, Sydney,
Hawkesbury Road, Westmead, NSW 2145, Australia. pfernandezpenas@med.usyd.edu.au
Allogeneic haematopoietic stem cell transplantation is increasingly used in the
treatment of malignant and non-malignant disorders. Despite ongoing advances in
the field, morbidity and mortality related to graft-versus-host disease remains a
major barrier to its application. Graft-versus-host disease is a
difficult-to-diagnose disease. Dermatologists are involved due to its diverse
cutaneous expression. In order to appropriately diagnose, classify and treat this
complex disease, knowledge of its expanding cutaneous expression is required.
This review provides a synopsis of the clinical manifestations of acute,
lichenoid and sclerodermatous phases of graft-versus-host disease with a look at
the current evidence surrounding its differential diagnosis.
DOI: 10.1111/j.1440-0960.2009.00577.x
PMID: 20148830 [Indexed for MEDLINE]
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