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Seité S, Bensadoun RJ, Mazer JM, et al.
Breast cancer (Dove Medical Press). Date of publication 2017 Nov 2;volume 9():551-557.
1. Breast Cancer (Dove Med Press). 2017 Nov 2;9:551-557. doi: 10.2147/BCTT.S149752. eCollection 2017. Prevention and treatment of acute and chronic radiodermatitis. Seité S(1), Bensadoun RJ(2), Mazer JM(3). Author information: (1)La Roche-Posay Laboratoire Dermatologique, Levallois-Perret. (2)Centre de Haute Energie (CHE), Nice. (3)Centre Laser International de la Peau, Paris, France. More than half the number of patients with cancer, who are treated with radiotherapy, will have radiodermatitis at some point during their treatment. Radiodermatitis either occurs early on in the treatment period or appears months or up to several years later. Acute radiodermatitis is a burn injury that varies in severity according to both treatment and inherent patient factors. Most acute radiodermatitis reactions resolve after several weeks but some reactions persist and can cause complications. Late-onset radiodermatitis is characterized by telangiectasia that forms on atrophic and fragile skin. These radiodermatitis reactions can have a significant negative impact on concomitant and subsequent therapeutic protocols and most particularly on the patient's quality of life. Today, treatment of radiodermatitis reactions is in its infancy. Although there is insufficient evidence available to form recommendations that would prevent or reduce radiodermatitis, some advances have been made using low level light therapy (LLLT) or vascular lasers to control the symptoms. Some recent preclinical and clinical research suggests that LLLT has biostimulating properties which allow the tissues to regenerate and heal faster, reduce inflammation, and prevent fibrosis. Also, in late-onset radiodermatitis pulsed dye laser treatment has been shown to be beneficial in clearing radiation-induced telangiectasia. In the absence of evidence-based recommendations, the objective of this paper is to review how to prevent or manage the symptoms of radiodermatitis reactions. DOI: 10.2147/BCTT.S149752 PMCID: PMC5677297 PMID: 29138594 Conflict of interest statement: Disclosure SS is an employee of La Roche-Posay Laboratoire Dermatologique, France. The authors report no other conflicts of interest in this work.
Appears in following Topics:
Radiation-induced Cutaneous Damage - Introduction and Assessment
Radiation-Induced Cutaneous Damage - Treatment, Prevention, Patient Education
Patient Education - Radiation-induced cutaneous damage - Late Effects
Patient Education - Radiation-induced cutaneous damage - Acute Effects