Lambade PN, Lambade D, Goel M, et al.
Oral and maxillofacial surgery. Date of publication 2013 Dec 1;volume 17(4):243-9.
1. Oral Maxillofac Surg. 2013 Dec;17(4):243-9. doi: 10.1007/s10006-012-0363-4. Epub
2012 Sep 28.
Osteoradionecrosis of the mandible: a review.
Lambade PN(1), Lambade D, Goel M.
Author information:
(1)Department of Oral and Maxillofacial Surgery, Swargiya Dadasaheb Kalmegh
Smruti Dental College and Hospital, Nagpur, 441110, Maharashtra, India,
drpravinlambade@gmail.com.
BACKGROUND: Osteoradionecrosis is a serious complication of radiotherapy that
often leads to severe facial deformity, pain, pathological fracture,
sequestration of devitalized bone, and orocutaneous fistulas. Preventive measures
for osteoradionecrosis are the best treatment plan to avoid osteoradionecrosis.
Radical surgery is indicated when conservative methods fail or when severe bone
and soft-tissue necrosis prevails.
CASE REPORT: The purpose of this paper is to explore the recent theories about
the definition, classification, incidence, and pathophysiology of
osteoradionecrosis (ORN) of the jaws. The predisposing and risk factors for the
development of osteoradionecrosis based on the literature review along with case
report are also discussed.
DISCUSSION: A better understanding on the risk factors responsible for causing
ORN and the underlying pathophysiology may improve our ability to prevent this
complication and help to improve the prognosis for those being treated for
osteoradionecrosis.
DOI: 10.1007/s10006-012-0363-4
PMID: 23053252 [Indexed for MEDLINE]
