Saber AA, Yahya KZ, Rao A, Castellano M, Cioroiu M, Grossi R, Tornambe RM, et al.
Journal of investigative surgery : the official journal of the Academy of Surgical Research. Date of publication 2005 Nov 1;volume 18(6):321-3.
1. J Invest Surg. 2005 Nov-Dec;18(6):321-3.
A new approach in the management of chronic nonhealing leg ulcers.
Saber AA(1), Yahya KZ, Rao A, Castellano M, Cioroiu M, Grossi R, Tornambe RM.
Author information:
(1)Department of Surgery, Michigan State University, Kalamazoo Center for Medical
Studies, Kalamazoo, Michigan 49008, USA. saber@kcms.msu.edu
Chronic leg ulcers are a major cause of mortality and morbidity. The efficacy of
hyperbaric oxygen treatment is being evaluated in the management of nonhealing
leg ulcers to improve skin graft survival. Twenty-seven patients with 36 chronic
leg ulcers were examined. Each wound received 12 preoperative hyperbaric oxygen
treatments, split-thickness skin grafting, followed by 12 postoperative
hyperbaric oxygen treatments. Wound transcutaneous oxygen tension measurements
(TCOM) were taken. The graft take was evaluated. At 18 months follow-up, 18 skin
grafts (50%) showed complete take, 15 (41.7%) demonstrated partial take, and 3
(8.3%) failed. Hyperbaric oxygen treatment is an effective adjunct in the
management of chronic leg ulcers, and its use resulted in increased graft take
and survival.
DOI: 10.1080/08941930500328821
PMID: 16319053 [Indexed for MEDLINE]
