Feldmeier JJ, Heimbach RD, Davolt DA, Court WS, Stegmann BJ, Sheffield PJ, et al.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, In.... Date of publication 1996 Dec 1;volume 23(4):205-13.
1. Undersea Hyperb Med. 1996 Dec;23(4):205-13.
Hyperbaric oxygen an adjunctive treatment for delayed radiation injuries of the
abdomen and pelvis.
Feldmeier JJ(1), Heimbach RD, Davolt DA, Court WS, Stegmann BJ, Sheffield PJ.
Author information:
(1)Department of Radiation Oncology, Wayne State University, Detroit, Michigan,
USA.
Comment in
Undersea Hyperb Med. 1997 Sep;24(3):215-6.
Radiation therapy is often utilized as adjunctive or primary treatment for
malignancies of the abdomen and pelvis. Radiation complications are infrequent,
but can be life threatening or significantly diminish the quality of life.
Radiation necrosis is an approved indication for hyperbaric oxygen (HBO2).
Previous publications have reported results in treating delayed radiation
injuries involving many sites. This paper reports the experience of a single
physician group in treating delayed injuries of the abdomen and/or pelvis.
Forty-four such patients have been treated since 1979. Of the 41 patients
available for follow up, 26 have healed; 6 failed to heal; and 9 patients had an
inadequate course of therapy (fewer than 20 treatments). Especially encouraging
was the resolution of fistulae in six of eight patients with only three requiring
surgery for closure. Overall, the success rate in patients receiving at least 20
HBO2 treatments was 81%. Hyperbaric oxygen is a useful adjunct in treatment of
delayed radiation injuries of the pelvis and abdomen.
PMID: 8989850 [Indexed for MEDLINE]
