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REGRANEX (becaplermin) Gel, 0.01%, 15g tube

REGRANEX Gel is a recombinant platelet-derived growth factor (PDGF). INTENDED USES: For use on diabetic neuropathic ulcers. CLAIMED FEATURES: is the only FDA-approved recombinant platelet-derived growth factor (PDGF) therapy. REGRANEX (becaplermin) Gel, 0.01% contains becaplermin, a human platelet-derived growth factor that is indicated for the treatment of lower extremity diabetic neuropathic ulcers that extend into the subcutaneous tissue or beyond and have an adequate blood supply. It is indicated as an adjunct to, and not a substitute for, good ulcer care practices.IMPORTANT SAFETY INFORMATION WARNING: INCREASED RATE OF MORTALITY SECONDARY TO MALIGNANCY - An increased rate of mortality secondary to malignancy was observed in patients treated with 3 or more tubes of REGRANEX (becaplermin) Gel, 0.01% in a postmarketing retrospective cohort study. REGRANEX Gel should only be used when the benefits can be expected to outweigh the risks. REGRANEX Gel should be used with caution in patients with known malignancy. OPTIONS: Gel, 0.01%, 15g tube

Product Information

Growth factors are substances that occur naturally in the body. They promote growth of new cells and healing of wounds. Studies show that treatment of diabetic foot ulcers with growth factors may improve the healing of ulcers, when compared with placebo or no growth factor. One example of growth factor that is produced in laboratory and made commercially available is becaplermin. Available as a topical gel, becaplermin is a human platelet-derived growth factor indicated for the treatment of lower extremity diabetic neuropathic ulcers, along with standard wound care.

Pricing and Suppliers

Is it covered by Medicare Part B?

Medicare Part D and Medicare Advantage plans cover becaplermin when all requirements are met.

How can I purchase this product?

Becaplermin topical gel can be purchased from pharmacies with a prescription from your provider. 

The table below shows highest and lowest Medicare pricing across the country
DescriptionMedicare DME co-payment Min / Max
Becaplermin gel 0.01%, 0.5 gm $0.00 / $0.00
Estimated out-of-pocket cost:

If your insurance does not cover this product, you can purchase it directly from any store. A list of online stores and prices is provided below for your convenience. For updated prices, find it on the internet at

Other Stores

* Indicates whether store accepts Medicare or commercial insurance, but may not apply to this specific product. See coding, coverage and reimubursement for more information.
The information on this handout is for your convenience and educational purposes only. All product claims and specifications are those of the product suppliers. It does not constitute medical advice or a guarantee for reimbursement. Prices may have changed and suppliers may not have product in stock. Please confirm accuracy and appropriateness of information with insurance carrier and product supplier. Clinician and WoundReference assume no liability for inaccuracies or misstatements about products and insurance coverage.