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Can we get this covered for HBOT despite not being related to radiation? Using code M27.8 Other specified diseases of the jaw? Further research leads me to "medication-related osteonecrosis of the jaw" for this patient's diagnosis, as well as avascular necrosis being used by some researchers. I point this out because osteoradionecrosis is the result of avascular, aseptic necrosis, which is of course a covered indication. This patient was diagnosed with metastatic prostate cancer and received Zoledronic Acid. By May 2022 he started to developed pain on the right upper maxillar area. Medication was discontinued in June 2022. He has been following with oral surgery who diagnosed with biphosphonate related osteonecrosis. He was started on IV antibiotics. Patient has been on several rounds of oral antibiotics with no resolution of his symptoms.
Jan 30, 2023 by Sarah Karson, RN, BSN
2 replies
Eugene Worth
MD, M.Ed., FABA, ABPM/UHM
Hi, Sarah ... thanks for the question. Let's clear up a couple of things before the "long-winded" answer. First, this condition (should you search the literature, and I recommend that you look at PubMed) is called BRONJ (Bisphosphonate Related OsteoNecrosis of the Jaw).

You are headed in the right direction, thinking about aseptic necrosis ... close, but no cigar. This is more like an osteomyelitis, but it has some of the characteristics of aseptic necrosis.

You've given the basis of treatment right there. If your physician documents as well as you have given in this thumbnail, you are well on your way.

For documentation, I would describe the relationship to the bisphosphonate, just as you have. Then, I would tell the story of refractory osteomyelitis ... as you did above. This patient has an osteo picture in the maxillary ridge, and has been treated with surgical debridement and several adequate courses of antibiotics (I think it would help if you had a positive bone culture ... but you can state that bone was sent to culture and had no growth) ...

Then, I would code this as a chronic refractory osteomyelitis and get your approval.

When you look this up for HBOT, the author is Freiberger. There were several papers from Duke on this topic with long-term followup.

Good luck!
Jan 30, 2023
Sarah Karson
RN, BSN
Thank you for the rapid response. I was thinking we could go down the chronic refractory osteomyelitis route. The patient is also completing an MRI, so I anticipate we will have this for support.

Thanks again!
Sarah, RN
Jan 30, 2023
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