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For subsequent HBO treatments for CRAO after your initial treatment do you always titrate up starting from 2.0 ATA and stopping where there is response or do you start at the ATA that was effective when you treated the first time? For example if patients vision was improving at 2.8 ATA during first treatment do you continue treating at 2.8 ATA for subsequent treatments or do you see if there is response at lower ATA's by titrating up again? Thank you
Aug 2, 2023 by Victor Meier, MD
1 replies
Mike White
MD, UHM, MMM, CWS
Victor,

You asked a great question. Unfortunately, the answer is not entirely clear. A literature search did not turn up a clear answer. The UHMS Hyperbaric Oxygen Therapy Indications Manual (14th ed) is also not entirely clear. However, if you read the first paragraph on page 19, it says " Should vision loss recur, aggressive use of intermittent normobaric oxygen as described in #2 or customized hyperbaric oxygen is indicated to preserve retinal function until CRA recanalization occurs. Hyperbaric treatments twice or three times daily may be necessary until the angiogram normalizes or the patient has no further improvement for three treatments." This would imply that you should go back to #2 (on page 17) and follow through with the other recommendations, ie. #3-#8, which would have you start back at 2.0 ATA and increase the pressure depending on patient response. I did speak with two UHM boarded physicians and they both said that in their experiences, most patients did not respond at 2.0 ATA and they both started subsequent HBO treatments at 2.4 ATA and increased the pressure as necessary. So, for subsequent treatments, you are going to have correlate clinically depending on patient presentation.
Aug 3, 2023
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