Castro DL, Santos VL, et al.
Revista da Escola de Enfermagem da U S P. Date of publication 2015 Oct 1;volume 49(5):858-63.
1. Rev Esc Enferm USP. 2015 Oct;49(5):858-63. doi: 10.1590/S0080-623420150000500021.
[Controlling wound odor with metronidazole: a systematic review].
[Article in Portuguese]
Castro DL(1), Santos VL(2).
Author information:
(1)Escola de Enfermagem, Universidade de São Paulo, São Paulo, SP, Brazil.
(2)Departamento de Enfermagem Médico-Cirúrgica, Escola de Enfermagem,
Universidade de São Paulo, São Paulo, SP, Brazil.
OBJECTIVE: Verifying the evidence of therapeutic efficacy in the topical
application of metronidazole for controlling wound odor.
METHODS: A systematic literature review, according to the Cochrane Collaboration
recommendations.
RESULTS: 329 articles were identified in the Cochrane, LILACS, SciELO, CINAHL and
PubMed databases, with 14 of them being included in the final sample. Two of the
studies were double-blind randomized clinical trial studies.
CONCLUSION: The actual effectiveness of metronidazole in controlling wound odor
cannot yet be evidenced due to the absence of strong evidence from studies on the
subject, despite clinical practice recommending its benefits.
DOI: 10.1590/S0080-623420150000500021
PMID: 26516758 [Indexed for MEDLINE]
